Methacrylic Acid

Methacrylic Acid

SCHEMBL524919

C=C(C)C(=O)O.C=CC(=O)OCCCCO.OCC(O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.50
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 2/20 0.50
HPGD P15428 1/20 0.46
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
HSD17B10 Q99714 1/20 0.39
THRB P10828 2/20 0.34
HCAR2 Q8TDS4 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
APP P05067 2/20 0.32
ACHE P22303 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL1471526 0.91 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL20875124 0.90 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL20875120 0.90 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Glycerin SCHEMBL28853681 0.89 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL27388671 0.86 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL731736 0.86 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL524918 0.85 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL28007666 0.83 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5176176 0.83 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL5028039 0.83 TSHR (0.73) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12038555-B2 Cationic contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2024-07-16 US disclosed
EP-4398004-A2 CATIONIC CONTACT LENS CooperVision International Limited (GB) 2024-07-10 EP disclosed
EP-4208741-B1 CATIONIC CONTACT LENS COOPERVISION INT LTD (GB) 2024-04-24 EP disclosed
US-20230408728-A1 CATIONIC CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2023-12-21 US disclosed
WO-2023242552-A1 CATIONIC CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2023-12-21 WO disclosed
EP-4208741-A1 CATIONIC CONTACT LENS CooperVision International Limited (GB) 2023-07-12 EP disclosed
CN-116391140-A Cationic contact lens 库博光学国际有限公司 2023-07-04 CN disclosed
WO-2022129871-A1 CATIONIC CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-06-23 WO disclosed
US-20220183433-A1 CATIONIC CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-06-16 US disclosed
EP-2681252-B1 SILICONE HYDROGEL CONTACT LENSES COOPERVISION INT HOLDING CO LP (BB) 2020-04-01 EP disclosed
US-20120220744-A1 Wettable Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US disclosed
US-20120220688-A1 Phosphine-Containing Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US disclosed
US-20120216489-A1 Silicone Hydrogel Contact Lenses With High Freezable Water Content COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US disclosed
US-20120220690-A1 Silicone Hydrogel Contact Lenses Having Acceptable Levels Of Energy Loss COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US disclosed
US-20120216488-A1 Silicone Hydrogel Contact Lenses And Related Compositions And Methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US disclosed
US-20120220743-A1 Dimensionally Stable Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US disclosed
US-20120218509-A1 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US disclosed
EP-2492720-A1 Wettable Silicone Hydrogel Contact Lenses CooperVision International Holding Company, LP (BB) 2012-08-29 EP disclosed
EP-2492719-A1 Dimensionally stable silicone hydrogel contact lenses CooperVision International Holding Company, LP (BB) 2012-08-29 EP disclosed
WO-2012013947-A1 SILICONE HYDROGEL OPHTHALMIC DEVICES MOLDED IN VINYL ALCOHOL COPOLYMER MOLDS AND RELATED METHODS GOODENOUGH NEIL (GB) 2012-02-02 WO disclosed