Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPR1 | P16066 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110620 | 0.90 | GAA (0.38) | ALDH1A1SMN1; SMN2MAPTGAAHCAR2 | |
| Trifluoroacetic Acid SCHEMBL6758189 | 0.83 | EPHX2 (0.44) | S1PR1S1PR3S1PR2ALDH1A1S1PR5 | |
| SCHEMBL28195253 | 0.80 | NAAA (0.44) | ALDH1A1MAPTGAAPOLBTDP1 | |
| SCHEMBL28158274 | 0.79 | MEN1 (0.36) | ALDH1A1SMN1; SMN2MAPTGAAPOLB | |
| SCHEMBL27924099 | 0.79 | NAAA (0.52) | TDP1 | |
| SCHEMBL27458393 | 0.78 | NAAA (0.55) | — | |
| SCHEMBL11070272 | 0.78 | NAAA (0.55) | — | |
| SCHEMBL28191838 | 0.78 | NAAA (0.55) | — | |
| SCHEMBL27546388 | 0.78 | NAAA (0.55) | — | |
| SCHEMBL27370301 | 0.78 | NAAA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855672-A1 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006104646-A1 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |