Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141453 | 0.80 | FPR2 (0.51) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL6030469 | 0.80 | FPR2 (0.51) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL29145873 | 0.80 | FPR2 (0.51) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL6029787 | 0.80 | FPR2 (0.51) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL6029789 | 0.80 | FPR2 (0.51) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL13485749 | 0.78 | GAA (0.47) | FPR2TBXAS1TAAR1FDPSGAA | |
| SCHEMBL6451096 | 0.78 | FPR2 (0.55) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL14387401 | 0.76 | FPR2 (0.48) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL5630316 | 0.76 | FPR2 (0.54) | FPR2TBXAS1NTRK1TAAR1KLK1 | |
| SCHEMBL1258259 | 0.76 | FPR2 (0.54) | FPR2TBXAS1NTRK1TAAR1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476438-B1 | OXA- AND THIADIAZOLES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | VERNALIS R&D LTD (GB) | 2007-04-18 | — | — | EP | disclosed |