SCHEMBL5249266

SCHEMBL5249266

CCCCNC(=O)OCC(C)(CNC)CNC

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.56
EPHX1 P07099 2/20 0.43
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5249829 0.87 ACHE (0.56) ACHEEPHX1ALOX15
SCHEMBL5248355 0.87 ACHE (0.56) ACHEEPHX1ALOX15
SCHEMBL5246050 0.86 ACHE (0.54) ACHEEPHX1ALOX15
SCHEMBL5248688 0.85 ACHE (0.58) ACHEEPHX1ALOX15
SCHEMBL5246152 0.84 SMN1; SMN2 (0.40) ACHEEPHX1
SCHEMBL5245969 0.83 ACHE (0.59) ACHEEPHX1ALOX15
SCHEMBL5246317 0.83 ACHE (0.54) ACHEEPHX1ALOX15
SCHEMBL13073328 0.81 ACHE (0.66) ACHEEPHX1ALOX15
SCHEMBL5247798 0.81 ACHE (0.47) ACHEEPHX1
SCHEMBL11219541 0.80 ACHE (0.59) ACHEEPHX1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379598-B1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AG (DE) 2007-09-12 EP disclosed
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed
EP-1379598-A1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AKTIENGESELLSCHAFT (DE) 2004-01-14 EP disclosed
WO-2002086000-A1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed