Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23257936 | 0.84 | ALOX5 (0.48) | CYP2A6DRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4912317 | 0.84 | CYP2A6 (0.50) | CYP2A6DRD1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2321931 | 0.82 | CYP2A6 (0.49) | CYP2A6DRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23782345 | 0.81 | ALOX5 (0.49) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL21912351 | 0.81 | SLC6A2 (0.47) | CYP2A6DRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2963101 | 0.80 | ALOX5 (0.50) | CYP2A6ALOX5CYP1A2PTGESLMNA | |
| SCHEMBL18612899 | 0.80 | CYP2A6 (0.50) | CYP2A6ALOX5CYP1A2PTGESLMNA | |
| SCHEMBL28019292 | 0.80 | CYP2A6 (0.50) | CYP2A6ALOX5CYP1A2PTGESLMNA | |
| SCHEMBL18313546 | 0.80 | CYP2A6 (0.50) | CYP2A6ALOX5CYP1A2PTGESLMNA | |
| SCHEMBL24689134 | 0.80 | ALOX5 (0.44) | CYP2A6DRD1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406605-B1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORP (KR) | 2007-09-19 | — | — | EP | disclosed |
| EP-1406605-A4 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORP (KR) | 2005-10-26 | — | — | EP | disclosed |
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION | 2005-03-24 | — | — | US | disclosed |
| US-6841569-B2 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1406605-A1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK Corporation (KR) | 2004-04-14 | — | — | EP | disclosed |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2003-04-24 | — | — | US | disclosed |
| WO-2003000247-A1 | CARBAMATES OF 2-HETEROCYCLIC-1,2-ETHANEDIOLS | SK CORPORATION (KR) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065193-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | CYP2A6 362/4885DRD1 102/4885SLC6A2 1992/4885 |
| US-20030078235-A1 | Carbamates of 2-heterocyclic-1,2-ethanediols | CNR2, CNR1, GRIN2C | CYP2A6 362/4885DRD1 102/4885SLC6A2 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.