Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404501 | 0.87 | KDM4E (0.55) | SMARCA2KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL4508356 | 0.86 | KDM4E (0.46) | SMARCA2KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL4408146 | 0.85 | SMARCA2 (0.48) | SMARCA2KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL4414892 | 0.85 | SMARCA2 (0.56) | SMARCA2KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL14293673 | 0.85 | KDM4E (0.45) | SMARCA2KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL4408981 | 0.85 | SMARCA2 (0.47) | SMARCA2KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL4409049 | 0.84 | KDM4E (0.51) | SMARCA2KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL14293606 | 0.83 | KDM4E (0.52) | SMARCA2KDM4EMEN1KMT2AALOX15 | |
| SCHEMBL5254340 | 0.81 | MEN1 (0.40) | SMARCA2KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL4756336 | 0.80 | ALDH1A1 (0.40) | SMARCA2KDM4EMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608352-A4 | POLYAMINE COMPOUNDS FOR TREATING CHEMOKINE RECEPTOR MEDIATED DISEASES | TAIGEN BIOTECHNOLOGY CO LTD (TW) | 2007-11-28 | — | — | EP | disclosed |
| EP-1608352-A1 | POLYAMINE COMPOUNDS FOR TREATING CHEMOKINE RECEPTOR MEDIATED DISEASES | Taigen Biotechnology (TW) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004089360-A1 | POLYAMINE COMPOUNDS FOR TREATING CHEMOKINE RECEPTOR MEDIATED DISEASES | TAIGEN BIOTECHNOLOGY (TW) | 2004-10-21 | — | — | WO | disclosed |