Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256488 | 0.90 | CTSS (0.47) | CTSS | |
| SCHEMBL5256704 | 0.89 | CTSS (0.47) | CTSSDRD2DRD4DRD3 | |
| SCHEMBL2972380 | 0.89 | CTSS (0.55) | CTSS | |
| SCHEMBL2972724 | 0.86 | CTSS (0.62) | CTSS | |
| SCHEMBL2978891 | 0.85 | CTSS (0.53) | CTSS | |
| SCHEMBL2971594 | 0.84 | CTSS (0.62) | CTSS | |
| SCHEMBL5254012 | 0.80 | CTSS (0.47) | CTSSDRD2DRD4DRD3 | |
| SCHEMBL2981133 | 0.78 | CTSS (0.52) | CTSSDRD2DRD4DRD3 | |
| SCHEMBL5788731 | 0.76 | CTSS (0.73) | CTSS | |
| SCHEMBL5254514 | 0.76 | CTSS (0.53) | CTSSDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309591-B1 | SUBSTITUTED PYRAZOLES | ORTHO MCNEIL PHARM INC (US) | 2007-01-24 | — | — | EP | claimed |