SCHEMBL5250418

SCHEMBL5250418

C=CC[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1N

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.42
SLC28A2 O43868 1/20 0.42
SLC29A1 Q99808 1/20 0.42
SLC28A3 Q9HAS3 1/20 0.42
P2RY14 Q15391 5/20 0.35
P2RY6 Q15077 6/20 0.32
P2RY2 P41231 4/20 0.32
PYGB P11216 1/20 0.32
P2RY4 P51582 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4970790 0.90 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5616451 0.81 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5144406 0.81 P2RY2 (0.55) P2RY6P2RY2P2RY4
SCHEMBL4849439 0.79 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4055613 0.79 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL1532519 0.79 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL8941498 0.79 SLC28A1 (0.49) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL28250490 0.78 SLC28A1 (0.48) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL18660236 0.77 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL23831167 0.77 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007120166-A2 MINIATURIZED IN VITRO PROTEIN EXPRESSION ARRAY UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-10-25 WO disclosed
US-20030219805-A1 Detection of alternative and aberrant mRNA splicing UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE 2003-11-27 US disclosed