Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 7/20 | 0.34 |
| ▸ | LGMN | Q99538 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266252 | 0.91 | GAA (0.45) | GAARAD52DPP4LGMNCDK1 | |
| Hydrochloric Acid SCHEMBL2535818 | 0.90 | GAA (0.44) | GAARAD52DPP4LGMNCDK1 | |
| Hydrochloric Acid SCHEMBL6401046 | 0.90 | GAA (0.44) | GAARAD52DPP4LGMNCDK1 | |
| SCHEMBL5245686 | 0.87 | GRM2 (0.37) | GAARAD52DPP4GRM2 | |
| Hydrochloric Acid SCHEMBL6714585 | 0.87 | GAA (0.42) | GAARAD52DPP4LGMNCDK1 | |
| SCHEMBL2927410 | 0.87 | RAD52 (0.46) | GAARAD52DPP4LGMNCDK1 | |
| Hydrochloric Acid SCHEMBL6495337 | 0.86 | RAD52 (0.45) | GAARAD52DPP4LGMNCDK1 | |
| SCHEMBL13515142 | 0.84 | GAA (0.40) | GAARAD52DPP4LGMN | |
| SCHEMBL12370012 | 0.84 | RAD52 (0.43) | GAARAD52DPP4LGMNCDK1 | |
| SCHEMBL2930438 | 0.84 | RAD52 (0.47) | GAARAD52DPP4LGMNCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428514-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | OREAL (FR) | 2007-09-19 | — | — | EP | claimed |
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | claimed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | claimed |
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | disclosed |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | GAA 4728/4885RAD52 481/4885DPP4 2362/4885 |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | GAA 4728/4885RAD52 481/4885DPP4 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.