Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268631 | 0.90 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| SCHEMBL2266681 | 0.90 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| SCHEMBL2272222 | 0.90 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| SCHEMBL2267999 | 0.90 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| SCHEMBL2269575 | 0.90 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| SCHEMBL2265915 | 0.90 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| Iodide SCHEMBL7141929 | 0.89 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| Iodide SCHEMBL2537383 | 0.89 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| Iodide SCHEMBL2540978 | 0.89 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT | |
| Iodide SCHEMBL6401114 | 0.89 | GRM2 (0.43) | GRM2DPP4KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428514-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | OREAL (FR) | 2007-09-19 | — | — | EP | claimed |
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | claimed |
| US-20040216244-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and an organic diacid, methods and uses | L'OREAL (FR) | 2004-11-04 | — | — | US | claimed |
| US-20040216246-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a polymer containing a fatty chain, methods and uses | L'OREAL (FR) | 2004-11-04 | — | — | US | claimed |
| US-20040216245-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a para-aminophenol, methods and uses | L'OREAL (FR) | 2004-11-04 | — | — | US | claimed |
| US-7101406-B2 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-09-05 | — | — | US | disclosed |
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | L'OREAL (FR) | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060112502-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | GRM2 4674/4885DPP4 2362/4885KDM4E 1328/4885 |
| US-20040216246-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a polymer containing a fatty chain, methods and uses | KRT18, PLIN5, PLIN1 | GRM2 4302/4885DPP4 2590/4885KDM4E 1845/4885 |
| US-20040216245-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a para-aminophenol, methods and uses | KRT18, CDC73, NUP205 | GRM2 4488/4885DPP4 1333/4885KDM4E 1079/4885 |
| US-20040221399-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a heterocyclic cationic direct dye, methods and uses | KRT18, CDC73, NUP205 | GRM2 4674/4885DPP4 2362/4885KDM4E 1328/4885 |
| US-20040216244-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and an organic diacid, methods and uses | KRT18, CDC73, DDC | GRM2 4712/4885DPP4 2152/4885KDM4E 1832/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | GRM2 4016/4885DPP4 3854/4885KDM4E 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.