Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5123530 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL3410324 | 0.69 | MEN1 (0.49) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL5119574 | 0.68 | TACR1 (0.46) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11000305 | 0.68 | KDM4E (0.33) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6643772 | 0.67 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL5123821 | 0.67 | MAOB (0.45) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL15358460 | 0.67 | HDAC3 (0.55) | ALDH1A1MEN1KMT2AMAPTPLA2G1B | |
| SCHEMBL5122580 | 0.66 | MAOB (0.41) | MEN1KMT2A | |
| SCHEMBL6645608 | 0.65 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EL3MBTL1HPGD | |
| SCHEMBL5121257 | 0.65 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AKDM4EL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441734-B1 | DIHYDROXYPYRIMIDINE CARBOXAMIDE INHIBITORS OF HIV INTEGRASE | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-02-28 | — | — | EP | disclosed |