⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183864 | 0.88 | — | — | |
| SCHEMBL20183860 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL7715636 | 0.62 | — | — | |
| SCHEMBL1783483 | 0.60 | CXCR4 (0.60) | — | |
| SCHEMBL13562 | 0.60 | — | — | |
| SCHEMBL770757 | 0.58 | — | — | |
| Bromide SCHEMBL9222450 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL3413512 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL15415090 | 0.58 | — | — | |
| Iodide SCHEMBL31112409 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151759-A1 | HETEROCYCLIC COMPOUNDS AS PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-11976058-B2 | Aromatic derivatives, preparation methods, and medical uses thereof | BIOARDIS LLC (US) | 2024-05-07 | — | — | US | disclosed |
| WO-2023239846-A1 | HETEROCYCLIC COMPOUNDS AS PI3KΑ INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023230262-A1 | TRICYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| US-20220169634-A1 | AROMATIC DERIVATIVES, PREPARATION METHODS, AND MEDICAL USES THEREOF | BIOARDIS LLC | 2022-06-02 | — | — | US | disclosed |
| CN-108137505-B | Nitrogen-containing heterocyclic compound | 富士胶片株式会社 | 2021-07-06 | — | — | CN | disclosed |
| US-10987349-B2 | Antitumor agent and bromodomain inhibitor | FUJIFILM CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| EP-3563851-B1 | ANTITUMOR AGENT AND BROMODOMAIN INHIBITOR | FUJIFILM CORP (JP) | 2021-04-21 | — | — | EP | disclosed |
| CN-111902400-A | Aromatic derivatives, process for their preparation and their medical use | 保仕健生物科技(上海)有限公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-3327004-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | FUJIFILM CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-20020052417-A1 | Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2002-05-02 | — | — | US | disclosed |
| EP-1189929-A2 | FACTOR VIIA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001094301-A2 | FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-13 | — | — | WO | disclosed |
| EP-1162194-A1 | Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use | Aventis Pharma Deutschland GmbH (DE) | 2001-12-12 | — | — | EP | disclosed |
| EP-1066236-A4 | PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE | RES FOUNDATION OF (US) | 2001-06-06 | — | — | EP | disclosed |
| EP-1066236-A1 | PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE | The Research Foundation of State University of New York (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-2000075172-A2 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999050214-A1 | PROCESS FOR HYDROCARBONYLATIONS IN SUPERCRITICAL CARBON DIOXIDE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-10-07 | — | — | WO | disclosed |
| US-5962744-A | USING CATALYST COMPLEX CONTAINING TRANSITION METAL AND PHOSPHITE LIGAND | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1999-10-05 | — | — | US | disclosed |