Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | HPGD | P15428 | 9/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10879529 | 0.82 | ADORA1 (0.42) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL2179728 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL10714412 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL7421874 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL2181401 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL7881545 | 0.71 | TAAR1 (0.54) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL12085224 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL3916264 | 0.70 | MAPT (0.53) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL7420557 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL12085233 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036078-B1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2007-05-09 | — | — | EP | disclosed |
| EP-1351962-B1 | THIENOPYRIMIDINE | MERCK PATENT GMBH (DE) | 2005-03-16 | — | — | EP | disclosed |
| EP-1355649-A2 | PHARMACEUTICAL FORMULATION CONTAINING PYRAZOLO 4,3-D]PYRIMIDINE AND NITRATES OR THIENOPYRIMIDINES AND NITRATES | MERCK PATENT GmbH (DE) | 2003-10-29 | — | — | EP | disclosed |
| EP-1347761-A2 | PHARMACEUTICAL FORMULATION CONTAINING THIENOPYRIMIDINES AND ANTITHROMBOTICS, CALCIUM ANTAGONISTS, PROSTAGLANDINS OR PROSTAGLANDIN DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-01 | — | — | EP | disclosed |
| EP-1337256-A2 | USE OF THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002060449-A2 | PHARMACEUTICAL FORMULATION CONTAINING PYRAZOLO[4,3-D]PYRIMIDINE AND NITRATES OR THIENOPYRIMIDINES AND NITRATES | MERCK PATENT GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |
| WO-2002049650-A2 | PHARMACEUTICAL FORMULATION CONTAINING THIENOPYRIMIDINES AND ANTITHROMBOTICS, CALCIUM ANTAGONISTS, PROSTAGLANDINS OR PROSTAGLANDIN DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-06-27 | — | — | WO | disclosed |
| WO-2002041896-A2 | USE OF THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2002-05-30 | — | — | WO | disclosed |
| EP-1036078-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028325-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1999-06-10 | — | — | WO | disclosed |