Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 20/20 | 0.67 |
| ▸ | CNR2 | P34972 | 18/20 | 0.66 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303166 | 0.91 | CNR1 (0.55) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628249 | 0.90 | CNR1 (0.67) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1627612 | 0.90 | CNR1 (0.70) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5255203 | 0.89 | CNR1 (0.59) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628947 | 0.88 | CNR1 (0.56) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5256623 | 0.88 | CNR1 (0.57) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628682 | 0.87 | CNR1 (0.73) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628652 | 0.86 | CNR1 (0.53) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5302654 | 0.85 | CNR1 (0.64) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5246850 | 0.81 | CNR1 (0.60) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558252-B1 | SUBSTITUTED FURO [2,3-B]PYRIDINE DERIVATIVES | MERCK & CO INC (US) | 2007-10-10 | — | — | EP | claimed |