Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.59 |
| ▸ | CNR2 | P34972 | 16/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.58 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256623 | 0.93 | CNR1 (0.57) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628249 | 0.92 | CNR1 (0.67) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5247164 | 0.90 | CNR1 (0.62) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5253181 | 0.89 | CNR1 (0.67) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628947 | 0.88 | CNR1 (0.56) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5303166 | 0.88 | CNR1 (0.55) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628652 | 0.86 | CNR1 (0.53) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5251945 | 0.83 | CNR1 (0.62) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL1628760 | 0.81 | CNR1 (0.87) | CNR1CNR2GABRA1GABRB1GABRA5 | |
| SCHEMBL5247149 | 0.81 | CNR1 (0.73) | CNR1CNR2GABRA1GABRB1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558252-B1 | SUBSTITUTED FURO [2,3-B]PYRIDINE DERIVATIVES | MERCK & CO INC (US) | 2007-10-10 | — | — | EP | claimed |