Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.74 |
| ▸ | ABL1 | P00519 | 2/20 | 0.61 |
| ▸ | BCR | P11274 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253281 | 0.86 | SRC (0.81) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5251689 | 0.86 | SRC (0.81) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5254975 | 0.85 | SRC (0.56) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5254965 | 0.82 | SRC (0.67) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5253791 | 0.82 | SRC (0.67) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5256325 | 0.78 | SRC (0.45) | SRCABL1BCR | |
| SCHEMBL5258438 | 0.77 | SRC (0.59) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6185291 | 0.77 | SRC (0.70) | SRCABL1BCRPRKCQ | |
| SCHEMBL5254056 | 0.76 | SRC (0.55) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5198196 | 0.76 | SRC (1.00) | SRCABL1BCREGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242382-B1 | TRICYCLIC PROTEIN KINASE INHIBITORS | WYETH CORP (US) | 2007-02-07 | — | — | EP | claimed |