Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515008 | 0.84 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL525985 | 0.84 | CTSA (0.48) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL524727 | 0.81 | CTSA (0.33) | CTSAACHEALDH1A1 | |
| SCHEMBL11514172 | 0.79 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL10897020 | 0.79 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL7739962 | 0.77 | CTSA (0.42) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL11514169 | 0.77 | CTSA (0.42) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL4736507 | 0.77 | CTSA (0.42) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL11516051 | 0.77 | CTSA (0.42) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL525808 | 0.75 | CTSA (0.40) | CTSAACHEALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598509-B1 | METHOD OF THE SYNTHESIS OF DIETHYL OR DIISOPROPYL HALOALKYLPHOSPHONATES AND DIETHYL OR DIISOPROPYL HALOALKYLOXYALKYLPHOSPHONATES | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY V V I (CZ) | 2018-02-07 | — | — | EP | disclosed |
| US-9187507-B2 | Acyclic nucleoside phosphonate derivatives and medical uses thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2015-11-17 | — | — | US | disclosed |
| EP-2598509-A1 | METHOD OF THE SYNTHESIS OF DIALKYL HALOALKYLPHOSPHONATES AND DIALKYL HALOALKYLOXYALKYLPHOSPHONATES | Ustav Organicke Chemie a Biochemie Akademie Ved Ceske Republiky, V.V.I. (CZ) | 2013-06-05 | — | — | EP | disclosed |
| US-20120322764-A1 | Acyclic Nucleoside Phosphonate Derivatives and Medical Uses Thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2012-12-20 | — | — | US | disclosed |
| EP-2511281-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES AND MEDICINE USES THEREOF | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China (CN) | 2012-10-17 | — | — | EP | disclosed |
| WO-2012013168-A1 | METHOD OF THE SYNTHESIS OF DIALKYL HALOALKYLPHOSPHONATES AND DIALKYL HALOALKYLOXYALKYLPHOSPHONATES | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY, v.v.i. (CZ) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322764-A1 | Acyclic Nucleoside Phosphonate Derivatives and Medical Uses Thereof | PNP, ENPP3, MTAP | CTSA 3891/4885ACHE 1953/4885ALDH1A1 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.