SCHEMBL525474

SCHEMBL525474

C=CCCCCCCCCCCCCCCCCC1=CC(=O)OC1=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
HDAC1 Q13547 2/20 0.34
LMNA P02545 2/20 0.34
HDAC4 P56524 1/20 0.33
ALOX15 P16050 1/20 0.33
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17180849 1.00 TDP1 (0.44) TDP1USP2ALDH1A1HPGDHDAC1
SCHEMBL11528390 0.85 USP2 (0.30) TDP1USP2ALDH1A1HPGD
SCHEMBL11509922 0.81 TSHR (0.48) TDP1USP2ALDH1A1HPGDALOX15
SCHEMBL3916829 0.79 CDC25A (0.49) ALDH1A1ALOX15MAPTTSHR
SCHEMBL8924182 0.77 ACHE (0.50)
SCHEMBL8921071 0.77 ACHE (0.50)
SCHEMBL6544689 0.77 ACHE (0.50)
SCHEMBL6413040 0.77 ACHE (0.50)
SCHEMBL19026087 0.77 ACHE (0.50)
SCHEMBL9697326 0.77 ACHE (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2226634-B1 Fluorescent colloidal nanocapsules, a process for their production and use in cells selection assays FOND ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2015-10-21 EP claimed
EP-2599147-A2 CARBON COATED LITHIUM TRANSITION METAL PHOSPHATE AND PROCESS FOR ITS MANUFACTURE Süd-Chemie IP GmbH & Co. KG (DE) 2013-06-05 EP disclosed
WO-2012013685-A2 CARBON COATED LITHIUM TRANSITION METAL PHOSPHATE AND PROCESS FOR ITS MANUFACTURE Süd-Chemie AG (DE) 2012-02-02 WO disclosed
EP-1675932-A2 ADDITIVE MIXTURE AS COMPONENT OF MINERAL OIL COMPOSITIONS LEUNA Polymer GmbH (DE) 2006-07-05 EP disclosed
WO-2005040316-A2 ADDITIVE MIXTURE AS COMPONENT OF MINERAL OIL COMPOSITIONS LEUNA POLYMER GMBH (DE) 2005-05-06 WO disclosed