Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254546 | 0.89 | MLLT1 (0.41) | PYGLCCKBRCCKAR | |
| SCHEMBL5257170 | 0.88 | MLLT1 (0.40) | PYGLPYGMCNR2CCKBRCCKAR | |
| SCHEMBL5257319 | 0.88 | F10 (0.47) | PYGLPYGM | |
| SCHEMBL5254513 | 0.88 | MLLT1 (0.54) | KDM4EHPGDHSD17B10PYGLPYGM | |
| SCHEMBL5259530 | 0.88 | PYGL (0.51) | PYGL | |
| SCHEMBL5258723 | 0.87 | KDM4E (0.43) | KDM4EHPGDPYGLPYGM | |
| SCHEMBL5255587 | 0.86 | F10 (0.35) | CHRNA7HTR3AKDM4EHPGDPYGL | |
| SCHEMBL5257371 | 0.85 | MLLT1 (0.38) | PYGLGHSR | |
| SCHEMBL5261814 | 0.84 | KMT2A (0.47) | KDM4E | |
| SCHEMBL5260311 | 0.81 | SRD5A1 (0.51) | KDM4EHPGDHSD17B10PYGLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453801-B1 | SUBSTITUTED 2-AMINO-CYCLOALKANECARBOXAMIDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | disclosed |