Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458529 | 0.81 | MAOB (0.33) | HTR2A | |
| SCHEMBL11026480 | 0.75 | MEN1 (0.32) | HTR2A | |
| SCHEMBL8776161 | 0.73 | HTR2A (0.33) | HTR2A | |
| SCHEMBL3389204 | 0.72 | HTR2A (0.35) | HTR2A | |
| SCHEMBL4307808 | 0.71 | HTR2A (0.34) | HTR2A | |
| SCHEMBL458495 | 0.71 | HTR2A (0.35) | HTR2A | |
| SCHEMBL458123 | 0.71 | HTR2A (0.34) | HTR2A | |
| SCHEMBL6521360 | 0.71 | HTR2A (0.35) | HTR2A | |
| SCHEMBL4290508 | 0.71 | HTR2A (0.35) | HTR2A | |
| SCHEMBL874497 | 0.71 | HTR2A (0.34) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805179-A2 | PREPARATION OF 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRID-2-ONES | Brystol-Myers Squibb Company (US) | 2007-07-11 | — | — | EP | claimed |
| WO-2006135425-A2 | PREPARATION OF 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRID-2-ONES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-21 | — | — | WO | claimed |
| EP-1805179-A2 | PREPARATION OF 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRID-2-ONES | Brystol-Myers Squibb Company (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006135425-A2 | PREPARATION OF 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRID-2-ONES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-21 | — | — | WO | disclosed |