Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389204 | 0.77 | HTR2A (0.35) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL455932 | 0.75 | HTR2A (0.34) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL4307808 | 0.75 | HTR2A (0.34) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL458495 | 0.75 | HTR2A (0.35) | HTR2AHTR2CHRH1 | |
| SCHEMBL6521360 | 0.75 | HTR2A (0.35) | HTR2AHTR2CHRH1 | |
| SCHEMBL4290508 | 0.75 | HTR2A (0.35) | HTR2AHTR2CHRH1 | |
| SCHEMBL874497 | 0.75 | HTR2A (0.34) | HTR2ARETHTR2CHRH1GRIN2D | |
| SCHEMBL8890669 | 0.72 | CHRNB2 (0.33) | HTR2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3634708 | 0.72 | PRCP (0.38) | HTR2AHTR2C | |
| SCHEMBL6272878 | 0.71 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |