Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 17/20 | 0.46 |
| ▸ | CD74 | P04233 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717307 | 0.88 | KCNK3 (0.54) | KCNK3CTSSCD74 | |
| SCHEMBL7626125 | 0.77 | KCNK3 (0.60) | KCNK3CTSSCD74 | |
| SCHEMBL4716707 | 0.72 | CTSS (0.64) | CTSSCD74 | |
| SCHEMBL4716819 | 0.72 | CTSS (0.64) | CTSSCD74 | |
| SCHEMBL12878789 | 0.71 | CTSS (0.63) | CTSSCD74 | |
| SCHEMBL1163858 | 0.71 | CTSS (0.63) | CTSSCD74 | |
| SCHEMBL2982361 | 0.71 | CTSS (0.60) | CTSSCD74 | |
| SCHEMBL1163905 | 0.69 | CTSS (0.54) | CTSSCD74 | |
| SCHEMBL4714854 | 0.69 | CTSS (0.54) | CTSSCD74 | |
| SCHEMBL2982272 | 0.68 | CTSS (0.56) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309592-B9 | SUBSTITUTED PYRAZOLES | ORTHO MCNEIL PHARM INC (US) | 2007-02-28 | — | — | EP | claimed |
| EP-1309592-B1 | SUBSTITUTED PYRAZOLES | ORTHO MCNEIL PHARM INC (US) | 2006-04-26 | — | — | EP | claimed |