Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 15/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571922 | 0.94 | CRHR1 (0.45) | CRHR1PDE10A | |
| SCHEMBL5252713 | 0.92 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL5571984 | 0.88 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL5547372 | 0.84 | CRHR1 (0.49) | CRHR1PDE10A | |
| SCHEMBL5551912 | 0.84 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL5550012 | 0.84 | CRHR1 (0.47) | CRHR1P2RX7 | |
| SCHEMBL5568978 | 0.83 | CRHR1 (0.45) | CRHR1PDE10A | |
| SCHEMBL5571952 | 0.83 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6013721 | 0.82 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL5571905 | 0.81 | CRHR1 (0.46) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583531-B1 | HETEROARYL-SUBSTITUTED PYRROLO[2, 3- B]PYRIDINE DERIVATIVES AS CRF RECEPTOR ANTAGONISTS | SB PHARMCO INC (US) | 2007-04-18 | — | — | EP | disclosed |