Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525985 | 0.77 | CTSA (0.48) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL114969 | 0.77 | CTSA (0.48) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL1003565 | 0.74 | TSHR (0.46) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL8626497 | 0.74 | CTSA (0.46) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL10739177 | 0.72 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL11333052 | 0.72 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL525701 | 0.72 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL3417732 | 0.72 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL10897020 | 0.72 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB | |
| SCHEMBL11514172 | 0.72 | CTSA (0.43) | CTSAACHEALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051874-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ZENTIVA, K.S. (CZ) | 2015-04-16 | — | — | WO | claimed |
| EP-2860185-A1 | An improved process for the preparation of Tenofovir disoproxil and pharmaceutically acceptable salts thereof | Zentiva, k.s. (CZ) | 2015-04-15 | — | — | EP | claimed |
| EP-2598509-B1 | METHOD OF THE SYNTHESIS OF DIETHYL OR DIISOPROPYL HALOALKYLPHOSPHONATES AND DIETHYL OR DIISOPROPYL HALOALKYLOXYALKYLPHOSPHONATES | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY V V I (CZ) | 2018-02-07 | — | — | EP | disclosed |
| WO-2015051874-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ZENTIVA, K.S. (CZ) | 2015-04-16 | — | — | WO | disclosed |
| EP-2860185-A1 | An improved process for the preparation of Tenofovir disoproxil and pharmaceutically acceptable salts thereof | Zentiva, k.s. (CZ) | 2015-04-15 | — | — | EP | disclosed |
| EP-2598509-A1 | METHOD OF THE SYNTHESIS OF DIALKYL HALOALKYLPHOSPHONATES AND DIALKYL HALOALKYLOXYALKYLPHOSPHONATES | Ustav Organicke Chemie a Biochemie Akademie Ved Ceske Republiky, V.V.I. (CZ) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013168-A1 | METHOD OF THE SYNTHESIS OF DIALKYL HALOALKYLPHOSPHONATES AND DIALKYL HALOALKYLOXYALKYLPHOSPHONATES | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY, v.v.i. (CZ) | 2012-02-02 | — | — | WO | disclosed |