Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114969 | 0.79 | CTSA (0.48) | CTSAACHEALDH1A1POLBKDM4E | |
| SCHEMBL525985 | 0.79 | CTSA (0.48) | CTSAACHEALDH1A1POLBKDM4E | |
| SCHEMBL7739962 | 0.78 | CTSA (0.42) | CTSAACHEALDH1A1POLBKDM4E | |
| SCHEMBL776262 | 0.78 | TSHR (0.42) | TSHRCTSAACHE | |
| SCHEMBL8626497 | 0.77 | CTSA (0.46) | CTSAACHEALDH1A1POLBKDM4E | |
| SCHEMBL525628 | 0.74 | CTSA (0.43) | CTSAACHEALDH1A1POLBKDM4E | |
| SCHEMBL11333052 | 0.74 | CTSA (0.43) | CTSAACHEALDH1A1POLBKDM4E | |
| SCHEMBL779227 | 0.74 | TSHR (0.43) | TSHR | |
| SCHEMBL10897020 | 0.74 | CTSA (0.43) | CTSAACHEALDH1A1POLBKDM4E | |
| SCHEMBL525701 | 0.74 | CTSA (0.43) | CTSAACHEALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699932-B | Polypropylene polymerization catalyst system and its application containing phosphoric acid ester external electron donor | 营口市向阳催化剂有限责任公司 | 2019-03-22 | — | — | CN | claimed |
| CN-106699932-A | Catalytic system containing phosphate external electron donors for polypropylene polymerization and application of catalytic system | 营口市向阳催化剂有限责任公司 | 2017-05-24 | — | — | CN | claimed |
| CN-101977920-A | Purification and preparation of phosphorus-containing compounds | SIGMA ALDRICH CO | 2011-02-16 | — | — | CN | claimed |
| US-20110021803-A1 | PURIFICATION AND PREPARATION OF PHOSPHORUS-CONTAINING COMPOUNDS | SIGMA-ALDRICH CO. NEWCO INC. | 2011-01-27 | — | — | US | claimed |
| EP-2265621-A2 | PURIFICATION AND PREPARATION OF PHOSPHORUS-CONTAINING COMPOUNDS | Sigma-Aldrich Co. (US) | 2010-12-29 | — | — | EP | claimed |
| WO-2009117583-A2 | PURIFICATION AND PREPARATION OF PHOSPHORUS-CONTAINING COMPOUNDS | SIGMA-ALDRICH, CO (US) | 2009-09-24 | — | — | WO | claimed |
| CN-109790350-A | Copolymer compositions with phosphonate group | 株式会社可乐丽 | 2019-05-21 | — | — | CN | disclosed |
| CN-106699932-B | Polypropylene polymerization catalyst system and its application containing phosphoric acid ester external electron donor | 营口市向阳催化剂有限责任公司 | 2019-03-22 | — | — | CN | disclosed |
| US-20170319604-A1 | THYROID HORMONE RECEPTOR AGONIST AND USE THEREOF | METABASIS THERAPEUTICS, INC. | 2017-11-09 | — | — | US | disclosed |
| CN-106699932-A | Catalytic system containing phosphate external electron donors for polypropylene polymerization and application of catalytic system | 营口市向阳催化剂有限责任公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-101977920-A | Purification and preparation of phosphorus-containing compounds | SIGMA ALDRICH CO | 2011-02-16 | — | — | CN | disclosed |
| US-20110021803-A1 | PURIFICATION AND PREPARATION OF PHOSPHORUS-CONTAINING COMPOUNDS | SIGMA-ALDRICH CO. NEWCO INC. | 2011-01-27 | — | — | US | disclosed |
| EP-2265621-A2 | PURIFICATION AND PREPARATION OF PHOSPHORUS-CONTAINING COMPOUNDS | Sigma-Aldrich Co. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009117583-A2 | PURIFICATION AND PREPARATION OF PHOSPHORUS-CONTAINING COMPOUNDS | SIGMA-ALDRICH, CO (US) | 2009-09-24 | — | — | WO | disclosed |
| CN-1059528-A | The new carbocyclic analogs of some nucleosides | MERRELL DOW PHARMA (US) | 1992-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170319604-A1 | THYROID HORMONE RECEPTOR AGONIST AND USE THEREOF | THRB, THRA, TSHR | TSHR 3/4885CTSA 2696/4885ACHE 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.