Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254517 | 0.86 | MLLT1 (0.55) | GHSRMLLT1CNR1PYGL | |
| SCHEMBL6840849 | 0.83 | GHSR (0.38) | GHSRMLLT1CNR1SLC2A1 | |
| SCHEMBL5256296 | 0.83 | GHSR (0.38) | GHSRMLLT1CNR1SLC2A1 | |
| SCHEMBL5260386 | 0.81 | HDAC3 (0.41) | HCRTR1 | |
| SCHEMBL5255164 | 0.81 | KDM4E (0.44) | PYGL | |
| SCHEMBL5256290 | 0.80 | GHSR (0.37) | GHSRMLLT1CNR1SLC2A1PYGL | |
| SCHEMBL5261818 | 0.79 | KMT2A (0.47) | — | |
| SCHEMBL5254550 | 0.79 | MLLT1 (0.41) | MLLT1PYGL | |
| SCHEMBL5257320 | 0.79 | F10 (0.48) | PYGL | |
| SCHEMBL5257173 | 0.79 | MLLT1 (0.41) | MLLT1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453801-B1 | SUBSTITUTED 2-AMINO-CYCLOALKANECARBOXAMIDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | disclosed |