Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257585 | 0.94 | HCRTR1 (0.31) | TGFBR1KMT2A | |
| SCHEMBL5255949 | 0.93 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL5258782 | 0.92 | TGFBR1 (0.31) | TGFBR1 | |
| SCHEMBL4764134 | 0.90 | TGFBR1 (0.30) | TGFBR1 | |
| SCHEMBL4762550 | 0.89 | AXL (0.30) | — | |
| SCHEMBL4763757 | 0.87 | TGFBR1 (0.36) | TGFBR1KMT2A | |
| SCHEMBL4763955 | 0.86 | — | — | |
| SCHEMBL4771564 | 0.85 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL4771805 | 0.85 | HSP90AB1 (0.35) | — | |
| SCHEMBL4770055 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648899-B1 | IMIDAZO-PYRIMIDINES AND TRIAZOLO-PYRIMIDINES: BENZODIAZEPINE RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2007-01-03 | — | — | EP | claimed |