⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL27723238 | 0.98 | CYP1A2 (0.48) | — | |
| Acrylic Acid SCHEMBL27777947 | 0.88 | CYP1A2 (0.41) | — | |
| SCHEMBL11399358 | 0.87 | NR1I2 (0.51) | — | |
| SCHEMBL11399361 | 0.87 | NR1I2 (0.51) | — | |
| SCHEMBL11301330 | 0.87 | NR1I2 (0.51) | — | |
| Methacrylic Acid SCHEMBL28783236 | 0.87 | MGAM (0.43) | — | |
| SCHEMBL3964566 | 0.86 | NR1I2 (0.59) | — | |
| O-Xylene SCHEMBL27482669 | 0.85 | CYP4F2 (0.49) | — | |
| SCHEMBL1306604 | 0.85 | TSHR (0.59) | — | |
| SCHEMBL9183882 | 0.83 | NR1I2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114570376-A | Catalyst for synthesizing menthone and method for synthesizing menthone | 安徽海华科技集团有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-107580596-B | Sulfimidoylpurine ketone compounds and derivatives for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-07-14 | — | — | CN | claimed |
| US-20200109144-A1 | Sulfonimidoylpurinone Compounds | HOFFMANN-LA ROCHE INC. (US) | 2020-04-09 | — | — | US | claimed |
| CN-109761912-A | A kind of synthetic method of polysubstituted pyrimidine derivative | 安徽诺全药业有限公司 | 2019-05-17 | — | — | CN | claimed |
| EP-3294740-A1 | NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | H. Hoffnabb-La Roche Ag (CH) | 2018-03-21 | — | — | EP | claimed |
| US-20170275286-A1 | Novel Sulfonimidoylpurinone Compounds and Derivatives for the Treatment and Prophylaxis of Virus Infection | HOFFMANN-LA ROCHE INC. (US) | 2017-09-28 | — | — | US | claimed |
| WO-2016180695-A1 | NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2016-11-17 | — | — | WO | claimed |
| US-20160326177-A1 | Novel Sulfonimidoylpurinone Compounds and Derivatives for the Treatment and Prophylaxis of Virus Infection | HOFFMANN-LA ROCHE INC. (US) | 2016-11-10 | — | — | US | claimed |
| EP-2598504-B1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2014-04-16 | — | — | EP | claimed |
| US-8476453-B2 | Process for the preparation of dimiracetam | NEUROTUNE AG (CH) | 2013-07-02 | — | — | US | claimed |
| EP-0628638-A2 | Process for preparing 2-amino-3-hydroxy acids | ELI LILLY AND COMPANY (US) | 1994-12-14 | — | — | EP | claimed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | claimed |
| WO-1990004393-A1 | PRODRUGS OF ANTIINFLAMMATORY 3-ACYL-2-OXINDOLE-1-CARBOXAMIDES | PFIZER INC. (US) | 1990-05-03 | — | — | WO | claimed |
| EP-0365194-A2 | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides | PFIZER INC. (US) | 1990-04-25 | — | — | EP | claimed |
| EP-0132851-B1 | 5-SUBSTITUTED(1,2,4)TRIAZOLO(1,5-C)PYRIMIDIN-2-AMINES | AMERICAN CYANAMID COMPANY (US) | 1989-10-04 | — | — | EP | claimed |
| EP-0132851-A1 | 5-Substituted(1,2,4)triazolo(1,5-c)pyrimidin-2-amines | AMERICAN CYANAMID COMPANY (US) | 1985-02-13 | — | — | EP | claimed |
| US-4474768-A | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor | PFIZER INC. (US) | 1984-10-02 | — | — | US | claimed |
| EP-0101186-A1 | N-methyl 11-aza-10-deoxo-10-dihydroerythromycin A, intermediates therefor and processes for their preparation | PFIZER INC. (US) | 1984-02-22 | — | — | EP | claimed |
| EP-0037241-A1 | Process for the preparation of erythromycylamine 11,12-carbonate | PFIZER INC. (US) | 1981-10-07 | — | — | EP | claimed |
| US-4283527-A | ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 1981-08-11 | — | — | US | claimed |