Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306604 | 0.94 | TSHR (0.59) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL7290192 | 0.92 | TSHR (0.62) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL1686744 | 0.92 | TSHR (0.62) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL20398941 | 0.92 | TSHR (0.62) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL89184 | 0.92 | TSHR (0.62) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL51878 | 0.92 | TSHR (0.62) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL362356 | 0.92 | TSHR (0.62) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL7946850 | 0.92 | TSHR (0.62) | NR1I2PGRADORA3PTGS2PDE4D | |
| Nonanal SCHEMBL29163124 | 0.87 | DGKA (0.58) | MAPTALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL525668 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574812-A | Benzenesulfonamide thiazole compounds and their use for the treatment of cancer | 国家医疗保健研究所 | 2024-08-30 | — | — | CN | claimed |
| CN-107876092-A | The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2018-04-06 | — | — | CN | claimed |
| CN-107417719-A | A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2017-12-01 | — | — | CN | claimed |
| CN-102311433-A | Method for preparing imidazo [1,2-a ] pyridine-3-acetic acid by one-pot method | NANJING UNIVERSITY OF TECHNOLOGY | 2012-01-11 | — | — | CN | claimed |
| EP-1001943-B1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-12-17 | — | — | EP | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| CN-1342157-A | Substituted pyrazoles ASP38 kinase inhibitors | SEARLE & CO (US) | 2002-03-27 | — | — | CN | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| US-5338786-A | Storage stability; containing a thiophene compounds and an arylsulphoryisocyanate compound | CHEMICAL INVESTMENTS, LTD. (GB) | 1994-08-16 | — | — | US | claimed |
| CN-114423758-B | Antibacterial compounds | 爱尔兰詹森科学公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119497712-A | Indane derivatives as MALT1 inhibitors | 希四克斯探索有限公司 | 2025-02-21 | — | — | CN | disclosed |
| EP-4452942-A1 | NANOMATERIALS COMPRISING DISULFIDES | Beam Therapeutics Inc. (US) | 2024-10-30 | — | — | EP | disclosed |
| US-20240335542-A1 | NANOMATERIALS COMPRISING DISULFIDES | BEAM THERAPEUTICS INC. | 2024-10-10 | — | — | US | disclosed |
| CN-118574812-A | Benzenesulfonamide thiazole compounds and their use for the treatment of cancer | 国家医疗保健研究所 | 2024-08-30 | — | — | CN | disclosed |
| US-4055714-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4045426-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4045427-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4042773-A | REACTION WITH POLYMERS | PENNWALT CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-3956269-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335542-A1 | NANOMATERIALS COMPRISING DISULFIDES | GPX4, GPX1, ABCB7 | NR1I2 3517/4885PGR 1492/4885ADORA3 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.