Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | USP8 | P40818 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185364 | 0.89 | FKBP1A (0.38) | NPC1RAB9AMAPTSMN1; SMN2MMP1 | |
| SCHEMBL5185359 | 0.89 | FKBP1A (0.38) | NPC1RAB9AMAPTSMN1; SMN2MMP1 | |
| SCHEMBL4693507 | 0.83 | MAPT (0.37) | NPC1RAB9AS1PR5MAPTSMN1; SMN2 | |
| SCHEMBL5253050 | 0.82 | NPC1 (0.35) | NPC1RAB9AS1PR5SMN1; SMN2MMP1 | |
| SCHEMBL4695526 | 0.80 | MEN1 (0.36) | ACENPC1RAB9AFFAR2 | |
| SCHEMBL20557593 | 0.79 | NPC1 (0.33) | NPC1RAB9AS1PR5MAPTUSP8 | |
| SCHEMBL4692474 | 0.73 | ESR1 (0.35) | ACE | |
| SCHEMBL5696945 | 0.73 | PSEN1 (0.41) | NPC1RAB9ASMN1; SMN2MMP1MMP3 | |
| SCHEMBL4144355 | 0.73 | POLB (0.38) | NPC1RAB9AS1PR5MAPTSMN1; SMN2 | |
| SCHEMBL5252852 | 0.72 | ACE (0.43) | ACEMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |