SCHEMBL525776

SCHEMBL525776

CCCCC(O)(S)S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9798351 0.91
SCHEMBL5575195 0.88 FDPS (0.48)
SCHEMBL28938302 0.88 FDPS (0.44)
Fluoride SCHEMBL31604076 0.86 FDPS (0.46)
SCHEMBL3801327 0.81
SCHEMBL524981 0.80
SCHEMBL11481245 0.79
SCHEMBL14742641 0.77 ESR1 (0.37)
SCHEMBL14743015 0.77 ESR1 (0.37)
SCHEMBL14743432 0.77 ESR1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2625216-B1 POLYMERISABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS NOVARTIS AG (CH) 2019-06-05 EP claimed
US-9109091-B2 Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups NOVARTIS AG (CH) 2015-08-18 US claimed
US-20150152228-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS ALCON INC. (CH) 2015-06-04 US claimed
US-8993651-B2 Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups NOVARTIS AG (CH) 2015-03-31 US claimed
EP-2625216-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS Novartis AG (CH) 2013-08-14 EP claimed
US-20120088843-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS ALCON INC. (CH) 2012-04-12 US claimed
WO-2012047961-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS NOVARTIS AG (CH) 2012-04-12 WO claimed
US-4992293-A Digestible fat substitutes in foods; side effect reduction NABISCO BRANDS, INC. (US) 1991-02-12 US claimed
EP-3635450-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-05-08 EP disclosed
US-11346982-B2 Silicone hydrogel contact lenses ALCON INC. (CH) 2022-05-31 US disclosed
CN-110709731-B Silicone hydrogel contact lenses 爱尔康公司 2022-05-24 CN disclosed
US-20210011197-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-01-14 US disclosed
US-10866344-B2 Silicone hydrogel contact lenses ALCON INC. (CH) 2020-12-15 US disclosed
EP-3635450-A1 SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-04-15 EP disclosed
US-20120088843-A1 POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS ALCON INC. (CH) 2012-04-12 US disclosed
US-20120088861-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-04-12 US disclosed
WO-2012047969-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2012-04-12 WO disclosed
US-20120029111-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-02-02 US disclosed
WO-2012016097-A2 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2012-02-02 WO disclosed
US-4992293-A Digestible fat substitutes in foods; side effect reduction NABISCO BRANDS, INC. (US) 1991-02-12 US disclosed