Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769921 | 0.93 | MAPT (0.31) | MAPT | |
| SCHEMBL4764094 | 0.92 | MAPT (0.33) | MAPT | |
| SCHEMBL4766506 | 0.91 | MAPT (0.33) | MAPT | |
| SCHEMBL4764078 | 0.90 | — | — | |
| SCHEMBL4769614 | 0.90 | PDE5A (0.31) | — | |
| SCHEMBL4762392 | 0.89 | MAPT (0.32) | MAPT | |
| SCHEMBL4765984 | 0.89 | PDE5A (0.30) | — | |
| SCHEMBL4767975 | 0.88 | TGFBR1 (0.30) | — | |
| SCHEMBL4767767 | 0.86 | AXL (0.34) | MAPT | |
| SCHEMBL4766072 | 0.86 | PDE5A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648899-B1 | IMIDAZO-PYRIMIDINES AND TRIAZOLO-PYRIMIDINES: BENZODIAZEPINE RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2007-01-03 | — | — | EP | claimed |