Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 8/20 | 0.35 |
| ▸ | CDK4 | P11802 | 8/20 | 0.33 |
| ▸ | RORB | Q92753 | 5/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547085 | 0.65 | CDC25A (0.60) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL3553146 | 0.64 | CDC25A (0.53) | CDC25ACDC25BCDC25CCDK4 | |
| SCHEMBL3550514 | 0.63 | CDK4 (0.43) | CDC25ACDC25BCDC25CCDK4NPC1 | |
| SCHEMBL17660296 | 0.60 | SMN1; SMN2 (0.42) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL2399177 | 0.59 | CDC25A (0.47) | CDC25ACDC25BCDC25CRORCRORB | |
| SCHEMBL3552749 | 0.59 | CDC25A (0.57) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL3552777 | 0.59 | CDC25A (0.59) | CDC25ACDC25BCDC25CRORCCDK4 | |
| SCHEMBL20428951 | 0.58 | GRM5 (0.49) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL3548778 | 0.57 | CDC25A (0.60) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL162901 | 0.57 | KMT2A (0.44) | MEN1KMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814879-A1 | DERIVATIVES OF 4,7-DIOXOBENZOTHIAZOLE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND THERAPEUTIC USES OF SAME | Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS (FR) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006051202-A1 | DERIVATIVES OF 4,7-DIOXOBENZOTHIAZOLE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND THERAPEUTIC USES OF SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) SAS (FR) | 2006-05-18 | — | — | WO | disclosed |