Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211876 | 0.81 | ATR (0.46) | ATRAAK1MAPKAPK2PSMB8MAP4K4 | |
| SCHEMBL15598649 | 0.80 | ATR (0.42) | ATRMAP4K4CYP17A1GAARAB9A | |
| SCHEMBL3577461 | 0.79 | LCK (0.51) | ATRCA1LCKCA12CA9 | |
| SCHEMBL1172821 | 0.79 | ATR (0.41) | ATRMAPKAPK2PSMB8GAARAB9A | |
| SCHEMBL28860053 | 0.79 | ATR (0.39) | ATRAAK1MAPKAPK2PSMB8MAP4K4 | |
| SCHEMBL30287245 | 0.78 | LCK (0.51) | ATRMAPKAPK2CA1CA2LCK | |
| SCHEMBL29741502 | 0.78 | HDAC1 (0.51) | ATRKMT2ALCKNAMPT | |
| SCHEMBL19233245 | 0.78 | ATR (0.40) | ATRAAK1MAPKAPK2MAP4K4CYP17A1 | |
| SCHEMBL28907016 | 0.77 | ATR (0.36) | ATRAAK1MAPKAPK2MAP4K4CYP17A1 | |
| SCHEMBL14877165 | 0.76 | MMP2 (0.44) | ATRPSMB8GAARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |