Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13483821 | 0.88 | KCNH2 (0.32) | CHRM2CHRM4CHRM1CHRM3KCNH2 | |
| SCHEMBL13952157 | 0.88 | KCNH2 (0.32) | CHRM2CHRM4CHRM1CHRM3KCNH2 | |
| SCHEMBL13483797 | 0.88 | KCNH2 (0.32) | CHRM2CHRM4CHRM1CHRM3KCNH2 | |
| SCHEMBL13930441 | 0.88 | KCNH2 (0.32) | CHRM2CHRM4CHRM1CHRM3KCNH2 | |
| SCHEMBL8546606 | 0.88 | KCNH2 (0.32) | CHRM2CHRM4CHRM1CHRM3KCNH2 | |
| SCHEMBL5955492 | 0.85 | GBA1 (0.31) | KCNH2 | |
| SCHEMBL3632801 | 0.81 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL4842716 | 0.81 | GNAO1 (0.39) | KCNH2 | |
| SCHEMBL4842706 | 0.81 | GNAO1 (0.39) | KCNH2 | |
| SCHEMBL4842723 | 0.81 | GNAO1 (0.39) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717230-B1 | FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| EP-1757594-A1 | QUINAZOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
| EP-1717230-A1 | FUSED-RING 4-OXOPYRIMIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | EP | disclosed |