⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396951 | 0.67 | TP53 (0.33) | — | |
| SCHEMBL275792 | 0.66 | HDAC3 (0.36) | — | |
| SCHEMBL1966649 | 0.65 | CA1 (0.41) | — | |
| SCHEMBL1277176 | 0.63 | TDP1 (0.32) | — | |
| SCHEMBL5807783 | 0.62 | ALDH1A1 (0.38) | — | |
| SCHEMBL269220 | 0.61 | — | — | |
| SCHEMBL37253 | 0.61 | — | — | |
| SCHEMBL1331033 | 0.61 | — | — | |
| SCHEMBL28732539 | 0.61 | TP53 (1.00) | — | |
| SCHEMBL8852429 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000398-A1 | 2,3-BENZOXAZIN DERIVATIVES AS NON-STEROIDAL GLUCOCORTICOID RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | claimed |
| WO-2006000401-A1 | SUBSTITUTED OXAZINES AS GLUCOCORTICOID RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | claimed |
| WO-2004071389-A2 | NON-STEROIDAL INFALMMATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-08-26 | — | — | WO | claimed |
| CN-113603868-B | Stille cross-coupling room-temperature polymerization method based on aryl dihalide and aryl dittany | 中国科学院大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-113603868-A | Stille cross-coupling room temperature polymerization method based on aryl dihalide and aryl distannane | 中国科学院大学 | 2021-11-05 | — | — | CN | disclosed |
| WO-2014194957-A1 | PYRENE COMPOUNDS FOR USE IN ORGANIC ELECTRONIC DEVICES | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts (DE) | 2014-12-11 | — | — | WO | disclosed |
| EP-1242426-B1 | GAMMA-HYDROXY-2-(FLUOROALKYLAMINOCARBONYL)-1-PIPERAZINEPENTANAMIDES AS HIV PROTEASE INHIBITORS | MERCK & CO INC (US) | 2007-10-31 | — | — | EP | disclosed |
| US-7223753-B2 | Diazabicyclic biaryl derivatives | NEUROSEARCH A/S (DK) | 2007-05-29 | — | — | US | disclosed |
| EP-1562945-B1 | 1,4-DIAZABICYCLO(3,2,2)NONANE DERIVATIVES, PREPARATION AND THERAPEUTICAL USE THEREOF | NEUROSEARCH AS (DK) | 2006-11-15 | — | — | EP | disclosed |
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0444889-A1 | Novel synthesis of carbapenem intermediates | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| WO-1990014330-A1 | NOVEL 8-SUBSTITUTED-2-AMINOTETRALINES | AKTIEBOLAGET ASTRA (SE) | 1990-11-29 | — | — | WO | disclosed |
| EP-0399982-A1 | Novel 8-substituted-2-amino-tetralines | Astra Aktiebolag (SE) | 1990-11-28 | — | — | EP | disclosed |
| US-4857539-A | Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents | STERLING DRUG INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0207453-A2 | Heterocyclic substituted-phenoxyalkyl-isoxazoles and-furans, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |
| EP-0001717-B1 | INSECTICIDAL COMPOSITIONS CONTAINING TETRAORGANOTIN COMPOUNDS AND METHOD FOR USING SAME | M & T CHEMICALS, INC. (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4212885-A | Insecticidal compositions containing certain tetraorganotin compounds and method for using same | M&T CHEMICALS INC. (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0001717-A2 | Insecticidal compositions containing tetraorganotin compounds and method for using same | M & T CHEMICALS, INC. (US) | 1979-05-02 | — | — | EP | disclosed |
| US-4138483-A | Insecticidal compositions containing certain tetraorganotin compounds and method for using same | M&T CHEMICALS INC. (US) | 1979-02-06 | — | — | US | disclosed |