Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.52 |
| ▸ | CNR2 | P34972 | 11/20 | 0.52 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264320 | 0.83 | CNR1 (0.66) | CNR1CNR2FDFT1UTS2R | |
| SCHEMBL5260356 | 0.81 | CNR1 (0.52) | CNR1CNR2FDFT1UTS2R | |
| SCHEMBL5264037 | 0.80 | CNR1 (0.65) | CNR1CNR2FDFT1 | |
| SCHEMBL5262773 | 0.77 | CNR1 (0.72) | CNR1CNR2FDFT1 | |
| SCHEMBL5263557 | 0.76 | FDFT1 (0.53) | CNR1CNR2FDFT1 | |
| SCHEMBL5262269 | 0.75 | CNR1 (0.63) | CNR1CNR2FDFT1 | |
| SCHEMBL5260009 | 0.75 | FDFT1 (0.68) | CNR1CNR2FDFT1UTS2R | |
| SCHEMBL6325790 | 0.74 | CNR1 (0.52) | CNR1CNR2FDFT1 | |
| SCHEMBL5373379 | 0.73 | CNR1 (0.59) | CNR1CNR2FDFT1UTS2R | |
| SCHEMBL5263940 | 0.73 | CNR1 (0.60) | CNR1CNR2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494997-A4 | SUBSTITUTED ARYL AMIDES | MERCK & CO INC (US) | 2007-04-11 | — | — | EP | claimed |
| JP-2005527586-A | — | — | 2005-09-15 | — | — | JP | claimed |
| EP-1494997-A1 | SUBSTITUTED ARYL AMIDES | Merck & Co., Inc. (US) | 2005-01-12 | — | — | EP | claimed |
| WO-2003087037-A1 | SUBSTITUTED ARYL AMIDES | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | claimed |
| EP-1494997-A4 | SUBSTITUTED ARYL AMIDES | MERCK & CO INC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1494997-A1 | SUBSTITUTED ARYL AMIDES | Merck & Co., Inc. (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087037-A1 | SUBSTITUTED ARYL AMIDES | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | disclosed |