Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.52 |
| ▸ | CNR2 | P34972 | 10/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259145 | 0.81 | ALDH1A1 (0.46) | HPGDMAPTALDH1A1KAT6ATP53 | |
| SCHEMBL5264037 | 0.80 | CNR1 (0.65) | CNR1CNR2HPGDFDFT1 | |
| SCHEMBL6325184 | 0.80 | TSHR (0.53) | CNR1CNR2FDFT1TP53MEN1 | |
| SCHEMBL3527214 | 0.78 | RAB9A (0.54) | CNR1CNR2HPGDMAPTALDH1A1 | |
| SCHEMBL13804732 | 0.78 | RAB9A (0.54) | CNR1CNR2HPGDMAPTALDH1A1 | |
| SCHEMBL5262773 | 0.77 | CNR1 (0.72) | CNR1CNR2FDFT1 | |
| SCHEMBL5260117 | 0.77 | CNR1 (0.54) | CNR1CNR2FDFT1 | |
| SCHEMBL6327703 | 0.77 | RAB9A (0.63) | CNR1CNR2HPGDMAPTALDH1A1 | |
| SCHEMBL5264320 | 0.77 | CNR1 (0.66) | CNR1CNR2FDFT1 | |
| SCHEMBL14119053 | 0.76 | KAT6A (0.48) | HPGDMAPTALDH1A1KAT6ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154202-A1 | Substituted aryl amides | MERCK & CO., INC. | 2005-07-14 | — | — | US | claimed |
| US-20050154202-A1 | Substituted aryl amides | MERCK & CO., INC. | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154202-A1 | Substituted aryl amides | CNR1, CNR2, FAAH | CNR1 1/4885CNR2 2/4885HPGD 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.