Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333747 | 0.91 | TLR7 (0.46) | GAAHTTTP53LMNATLR7 | |
| SCHEMBL5364616 | 0.83 | TLR7 (0.48) | GAAHTTTP53LMNATLR7 | |
| SCHEMBL1895809 | 0.82 | TLR7 (0.41) | TLR7TLR8SMN1; SMN2CNR1CNR2 | |
| SCHEMBL5106169 | 0.82 | TLR7 (0.40) | TLR7TLR8CNR2 | |
| SCHEMBL25962881 | 0.82 | TLR7 (0.49) | GAAHTTTP53LMNATLR7 | |
| SCHEMBL1951281 | 0.82 | GAA (0.47) | GAAHTTTP53LMNATLR7 | |
| SCHEMBL1951282 | 0.82 | GAA (0.47) | GAAHTTTP53LMNATLR7 | |
| SCHEMBL3093082 | 0.82 | GNRHR (0.39) | TLR7TLR8CNR2 | |
| SCHEMBL1960054 | 0.81 | TLR7 (0.42) | GAAHTTTP53LMNATLR7 | |
| SCHEMBL2897450 | 0.81 | TLR7 (0.43) | GAAHTTTP53LMNATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341790-B1 | SULFONAMIDO ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2007-02-14 | — | — | EP | disclosed |