Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897450 | 0.90 | TLR7 (0.43) | TLR7TLR8CNR2CNR1GAA | |
| SCHEMBL3666095 | 0.88 | TLR8 (0.41) | TLR7TLR8KDM4EALDH1A1 | |
| SCHEMBL4165388 | 0.85 | CNR1 (0.43) | TLR7TLR8CNR2CNR1GAA | |
| SCHEMBL1951281 | 0.83 | GAA (0.47) | TLR7TLR8CNR2CNR1GAA | |
| SCHEMBL1951282 | 0.83 | GAA (0.47) | TLR7TLR8CNR2CNR1GAA | |
| SCHEMBL4152852 | 0.83 | PDE4A (0.41) | TLR7TLR8CNR2CNR1GAA | |
| SCHEMBL1960247 | 0.82 | TLR7 (0.47) | TLR7TLR8CNR2CNR1GAA | |
| SCHEMBL5259308 | 0.81 | GAA (0.40) | TLR7TLR8CNR2CNR1GAA | |
| SCHEMBL5617629 | 0.81 | TLR7 (0.42) | TLR7TLR8CNR2CNR1LMNA | |
| SCHEMBL5364616 | 0.81 | TLR7 (0.48) | TLR7CNR2GAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507237-A1 | IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068233-A1 | IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-06-09 | — | — | WO | disclosed |