Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262864 | 0.99 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CNR1MAPT | |
| SCHEMBL5261136 | 0.76 | CNR1 (0.46) | CNR1HTR2AHTR2C | |
| SCHEMBL5259512 | 0.76 | CNR1 (0.52) | CNR1MAPTKIF11HTR2AHTR2C | |
| SCHEMBL5260291 | 0.75 | CNR1 (0.53) | CNR1MAPTHTR2AHTR2CDRD2 | |
| SCHEMBL5260371 | 0.74 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL5259219 | 0.71 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5262177 | 0.70 | MAPT (0.56) | CNR1MAPTHTR2AHTR2CDRD2 | |
| SCHEMBL6790586 | 0.69 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL5258567 | 0.68 | CNR1 (0.54) | CNR1MAPTHTR2AHTR2CDRD2 | |
| SCHEMBL5258234 | 0.67 | CNR1 (0.52) | CNR1MAPTHTR2AHTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261585-B1 | SUBSTITUTED INDOLE MANNICH BASES | GRUENENTHAL GMBH (DE) | 2007-09-26 | — | — | EP | claimed |