Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.56 |
| ▸ | CHRNG | P07510 | 4/20 | 0.56 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.56 |
| ▸ | CHRND | Q07001 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072701 | 0.78 | SLC6A2 (0.69) | SLC6A2SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL10392066 | 0.78 | ALDH1A1 (0.52) | SLC6A2SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL8254272 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL4936216 | 0.77 | CHRM2 (0.61) | SLC6A2SLC6A3SLC6A4ALDH1A1KDM4E | |
| SCHEMBL13304408 | 0.77 | CHRM2 (0.61) | SLC6A2SLC6A3SLC6A4ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL10728832 | 0.77 | SLC6A2 (0.68) | SLC6A2SLC6A3SLC6A4CHRNB4CHRNA3 | |
| Bromide SCHEMBL13729160 | 0.77 | SLC6A2 (0.68) | SLC6A2SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL10734713 | 0.77 | CYP2C9 (0.65) | ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28360223 | 0.76 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4CHRNB4CHRNA3 | |
| SCHEMBL11037118 | 0.76 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770636-B2 | CENTRAL NERVOUS SYSTEM DISORDERS THERAPY | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20020042410-A1 | Phenyl-and phenylalkyl-substituted ethanolamines and ethylenediamines | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042410-A1 | Phenyl-and phenylalkyl-substituted ethanolamines and ethylenediamines | AOC2, CYC1, CYCS | SLC6A2 1559/4885SLC6A3 782/4885SLC6A4 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.