Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5258064 | 0.93 | KDM4E (0.55) | KDM4EHSD17B10NPSR1MAPK1HTT | |
| SCHEMBL4838091 | 0.90 | NPSR1 (0.49) | KDM4EHSD17B10NPSR1MAPK1HTT | |
| SCHEMBL5257212 | 0.89 | MAPT (0.54) | KDM4EHSD17B10NPSR1MAPK1HTT | |
| SCHEMBL4840594 | 0.86 | NPSR1 (0.46) | KDM4EHSD17B10NPSR1MAPK1HTT | |
| SCHEMBL4835082 | 0.86 | NPSR1 (0.45) | KDM4EHSD17B10NPSR1MAPK1HTT | |
| SCHEMBL4839497 | 0.86 | NPSR1 (0.54) | KDM4EHSD17B10NPSR1MAPK1USP2 | |
| SCHEMBL4834088 | 0.85 | DRD3 (0.63) | DRD2DRD3 | |
| SCHEMBL4839716 | 0.85 | ATM (0.54) | KDM4EHSD17B10NPSR1ALDH1A1KMT2A | |
| SCHEMBL4843775 | 0.85 | HSP90AB1 (0.57) | KDM4EHSD17B10NPSR1MAPK1HTT | |
| SCHEMBL4843946 | 0.85 | ALDH1A1 (0.54) | KDM4EHSD17B10NPSR1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | claimed |