Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498810 | 0.89 | KCNH2 (0.67) | KCNH2MEN1KMT2ASLC2A1 | |
| SCHEMBL14341212 | 0.89 | KCNH2 (0.67) | KCNH2MEN1KMT2ASLC2A1 | |
| SCHEMBL5260170 | 0.88 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| SCHEMBL5260199 | 0.81 | KCNH2 (0.76) | KCNH2SLC2A1 | |
| SCHEMBL5261624 | 0.80 | KCNH2 (0.79) | KCNH2 | |
| SCHEMBL5260215 | 0.78 | KCNH2 (0.76) | KCNH2SLC2A1 | |
| SCHEMBL5264690 | 0.77 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL5265007 | 0.77 | KCNH2 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL14341454 | 0.76 | KCNH2 (0.70) | KCNH2SLC2A1 | |
| SCHEMBL5262423 | 0.75 | KCNH2 (0.59) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399443-B1 | NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2007-12-12 | — | — | EP | claimed |