Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498804 | 0.88 | KCNH2 (0.78) | KCNH2SLC2A1 | |
| SCHEMBL5261624 | 0.88 | KCNH2 (0.79) | KCNH2 | |
| SCHEMBL5260215 | 0.87 | KCNH2 (0.76) | KCNH2SLC2A1 | |
| SCHEMBL5260199 | 0.87 | KCNH2 (0.76) | KCNH2SLC2A1 | |
| SCHEMBL5260522 | 0.85 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL5259762 | 0.82 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL5265007 | 0.82 | KCNH2 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL5260170 | 0.80 | KCNH2 (0.55) | KCNH2SLC2A1 | |
| SCHEMBL5262423 | 0.78 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL5260283 | 0.77 | KCNH2 (0.52) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399443-B1 | NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2007-12-12 | — | — | EP | claimed |