Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | OSBP | P22059 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.54 |
| ▸ | GBA1 | P04062 | 2/20 | 0.52 |
| ▸ | UGCG | Q16739 | 2/20 | 0.52 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.49 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830883 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL31701636 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL9978550 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL9978568 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL12207653 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL2830884 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL9978647 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL9978599 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL2832560 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 | |
| SCHEMBL31700942 | 1.00 | DPP4 (0.76) | DPP4POLBPOLA1CYP46A1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1837345-A1 | Pharmaceutical compositions comprising cholesteryl-alpha-glucosyltransferase for the treatment of Helicobacteri pylori infections | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2007-09-26 | — | — | EP | disclosed |