SCHEMBL526047

SCHEMBL526047

CCCCCCCCCCCCCCCCCCCC.CCCCCCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
KDM4E B2RXH2 1/20 1.00
DUSP3 P51452 1/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
DGKA P23743 1/20 0.82
MAPT P10636 1/20 0.69
FAAH O00519 2/20 0.68
PRKCA P17252 3/20 0.66
PRKCE Q02156 1/20 0.66
PRKCQ Q04759 1/20 0.66
PRKCD Q05655 1/20 0.66
ENPP2 Q13822 4/20 0.65
LPAR6 P43657 1/20 0.65
LPAR1 Q92633 1/20 0.65
LPAR4 Q99677 1/20 0.65
LPAR5 Q9H1C0 1/20 0.65
LPAR2 Q9HBW0 1/20 0.65
LPAR3 Q9UBY5 1/20 0.65
ALDH1A1 P00352 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monoctanoin Component B SCHEMBL22366087 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
Glycerol Monolaurate SCHEMBL16042 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL595035 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL21685815 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL21685794 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
Octane SCHEMBL5181039 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL3503441 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
2',3'-Dihydroxy Propyl Pentadecanoate SCHEMBL401287 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
Glyceryl Monostearate SCHEMBL5719482 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL16538137 1.00 LMNA (1.00) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114040746-B Oil-in-water type cleansing cosmetic 陶氏东丽株式会社 2024-02-27 CN disclosed
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof DOW SILICONES CORPORATION (US) 2023-11-21 US disclosed
EP-2492301-B1 NOVEL CO-MODIFIED ORGANOPOLYSILOXANE DOW TORAY CO LTD (JP) 2023-03-29 EP disclosed
CN-115052932-A Composition, method for preparing copolymer and end use of copolymer 美国陶氏有机硅公司 2022-09-13 CN disclosed
CN-108137820-B Cosmetic composition, cosmetic and external preparation for skin 陶氏东丽株式会社 2022-05-27 CN disclosed
CN-114040746-A Oil-in-water type cleansing cosmetic 陶氏东丽株式会社 2022-02-11 CN disclosed
EP-3906281-A1 COMPOSITION, METHOD OF PREPARING COPOLYMER, AND METHODS AND END USES THEREOF Dow Silicones Corporation (US) 2021-11-10 EP disclosed
WO-2020142388-A1 COMPOSITION, METHOD OF PREPARING COPOLYMER, AND METHODS AND END USES THEREOF DOW SILICONES CORPORATION (US) 2020-07-09 WO disclosed
US-10172779-B2 Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same DOW CORNING TORAY CO., LTD. (JP) 2019-01-08 US disclosed
EP-2492300-B1 NOVEL ORGANOPOLYSILOXANE COPOLYMER DOW CORNING TORAY CO LTD (JP) 2018-10-03 EP disclosed
CN-102648264-A Thickening or gelling agent for oil-based raw materials DOW CORNING TORAY CO LTD 2012-08-22 CN disclosed
CN-102639542-A Linear and cyclic siloxanes and cosmetic compositions made thereof DOW CORNING TORAY CO LTD 2012-08-15 CN disclosed
WO-2012091155-A1 COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2012-07-05 WO disclosed
WO-2012015070-A1 COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2012-02-02 WO disclosed
WO-2012015069-A1 COSMETIC FOR HAIR CONTAINING SUGAR ALCOHOL-MODIFIED SILICONE DOW CORNING TORAY CO., LTD. (JP) 2012-02-02 WO disclosed
WO-2011136394-A1 POWDER TREATMENT AGENT COMPRISING SUGAR ALCOHOL -MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011136393-A1 ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL -BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011136397-A1 NOVEL ORGANOPOLYSILOXANE, SURFACTANT, EMULSION COMPOSITION, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL, GELLING AGENT, GEL COMPOSITION, AND COSMETIC RAW MATERIAL COMPRISING NOVEL ORGANOPOLYSILOXANE, AS WELL AS, PREPARATION FOR EXTERNAL USE AND COSMETIC COMPRISING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011078407-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011068250-A1 LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof BRS3, OXSR1, OXER1 LMNA 1782/4885KDM4E 4721/4885DUSP3 4224/4885
US-10172779-B2 Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same DCLRE1A, MC1R, ADGRE5 LMNA 2717/4885KDM4E 4508/4885DUSP3 4775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.