Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525997 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL5636629 | 0.76 | KMT2A (0.64) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL38654855 | 0.75 | KMT2A (0.67) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL525996 | 0.74 | KMT2A (0.51) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL30649118 | 0.74 | KMT2A (0.71) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL4389696 | 0.74 | KMT2A (0.71) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL2360330 | 0.74 | KMT2A (0.61) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL3546124 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL2747531 | 0.73 | KMT2A (0.64) | ALDH1A1KMT2AMEN1CYP19A1HTT | |
| SCHEMBL38655017 | 0.72 | KMT2A (0.56) | ALDH1A1KMT2AMEN1CYP19A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598507-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014147-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-02 | — | — | WO | disclosed |