Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692749 | 0.86 | NPC1 (0.52) | KMT2AMEN1PABPC1NPC1RAB9A | |
| SCHEMBL5691055 | 0.77 | RAB9A (0.63) | KMT2AMEN1PABPC1NPC1RAB9A | |
| SCHEMBL5692781 | 0.73 | CACNA1F (0.49) | KMT2AALDH1A1CHRM4 | |
| SCHEMBL5691252 | 0.73 | RAB9A (0.71) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5692659 | 0.72 | HSD17B10 (0.68) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11150597 | 0.71 | ATM (0.69) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6633618 | 0.71 | KMT2A (0.89) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6638013 | 0.70 | TSHR (0.73) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL655417 | 0.70 | RAB9A (0.51) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8990610 | 0.69 | NPC1 (0.52) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824862-A1 | SILICON COMPOUNDS AND THEIR USE | Takeda Cambridge Limited (GB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006064263-A1 | SILICON COMPOUNDS AND THEIR USE | TAKEDA CAMBRIDGE LIMITED (GB) | 2006-06-22 | — | — | WO | disclosed |
| EP-1648906-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE | Paradigm Therapeutics Limited (GB) | 2006-04-26 | — | — | EP | disclosed |
| EP-1644385-A1 | SILICON COMPOUNDS AND THEIR USE | Paradigm Therapeutics Limited (GB) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005005443-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE | PARADIGM THERAPEUTICS LTD. (GB) | 2005-01-20 | — | — | WO | disclosed |
| WO-2005005442-A1 | SILICON COMPOUNDS AND THEIR USE | PARADIGM THERAPEUTICS LTD. (GB) | 2005-01-20 | — | — | WO | disclosed |