Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.54 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255889 | 0.92 | ITGB1 (0.54) | ITGB1ITGA4 | |
| SCHEMBL5254675 | 0.92 | ITGB1 (0.54) | ITGB1ITGA4 | |
| SCHEMBL5224413 | 0.89 | ITGB1 (0.57) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5256390 | 0.84 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5263621 | 0.83 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5263618 | 0.83 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5257997 | 0.83 | ITGB1 (0.56) | ITGB1ITGA4 | |
| SCHEMBL5257169 | 0.83 | ITGB1 (0.56) | ITGB1ITGA4 | |
| SCHEMBL5254682 | 0.81 | ITGB1 (0.53) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5224351 | 0.81 | ITGA4 (0.66) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |